10 hours ago

By estimating the age of origin of more than 45 million human genetic variants from population genome sequencing data, this study reveals the influence of selection and demography on the human genome and releases the Atlas of Variant Age as a public online database.

 1 day and 1 hour ago

A little-known start-up helps law enforcement match photos of unknown people to their online images — and “might lead to a dystopian future or something,” a backer says.

 1 day and 16 hours ago

Officials altered a photo of the 2017 Women’s March to avoid “political controversy.”

 1 day and 16 hours ago

The widespread establishment of statistics departments in the United States during the mid-20th century can be traced to a presentation by Harold Hotelling in the Berkeley Symposium on Mathematical…

 2 days ago

Recent experimental advances have enabled high-throughput single-cell measurement of gene expression, chromatin accessibility and DNA methylation. We previously used integrative nonnegative matrix factorization (iNMF) to jointly learn interpretable low-dimensional representations from multiple single-cell datasets using dataset-specific and shared metagene factors. These factors provide a principled, quantitative definition of cellular identity and how it varies across biological contexts. Ho...

 2 days and 3 hours ago

The JPM circus has too many tents, while other industry events have too few. Maybe it's time to reconsider what these conferences are all about.

 2 days and 4 hours ago

The Nikon Small World Photomicrography Competition has been held for forty-five years now, celebrating the mesmerizing microscopic world and allowing scientists and enthusiasts alike to share their scientific and stunning images.

 2 days and 4 hours ago

Gwyneth Paltrow's "the goop lab" is now airing on Netflix. The first three episodes were so boring I couldn't manage to watch any more.

 2 days and 19 hours ago

In a dramatic reversal, a European Patent Office’s board of appeal has upheld the revocation of a Broad Institute CRISPR/Cas9 patent.

 2 days and 20 hours ago

"I don’t think it’s fair criticism," says Lilly's Mike Mason. "When we launched LisPro, we didn’t say this was the solution for the marketplace."

 2 days and 21 hours ago

In a recent letter to the White House, a group of corporate publishers and scholarly organizations implore the president to leave intact…

 2 days and 22 hours ago

The most detailed study of sepsis shows it is a much bigger problem than previously thought.

 2 days and 23 hours ago

PREDICTOR Warren Buffett